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FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural...

FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251046724

FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells

About this item

Full title

FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2019-04, Vol.15 (4), p.e1008097-e1008097

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Maintenance of a healthy proteome is essential for cellular homeostasis and loss of proteostasis is associated with tissue dysfunction and neurodegenerative disease. The mechanisms that support proteostasis in healthy cells and how they become defective during aging or in disease states are not fully understood. Here, we investigate the transcripti...

Alternative Titles

Full title

FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2251046724

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251046724

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1008097

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