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The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence...

The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251084645

The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans

About this item

Full title

The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2018-08, Vol.14 (8), p.e1007220-e1007220

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The battle for iron between invading microorganisms and mammalian hosts is a pivotal determinant of the outcome of infection. The pathogenic fungus, Cryptococcus neoformans, employs multiple mechanisms to compete for iron during cryptococcosis, a disease primarily of immunocompromised hosts. In this study, we examined the role of endocytic traffick...

Alternative Titles

Full title

The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2251084645

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251084645

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1007220

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