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Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA sec...

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA sec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251095802

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Human Group IIA secreted phospholipase A2 (hGIIA) is an acute phase protein with bactericidal activity against Gram-positive bacteria. Infection models in hGIIA transgenic mice have suggested the importance of hGIIA as an innate defense mechanism against the human pathogens Group A Streptococcus (GAS) and Group B Streptococcus (GBS). Compared to ot...

Alternative Titles

Full title

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2251095802

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251095802

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1007348

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