Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudom...
Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Pseudomonas aeruginosa utilizes the Type II secretion system (T2SS) to translocate a wide range of large, structured protein virulence factors through the periplasm to the extracellular environment for infection. In the T2SS, five pseudopilins assemble into the pseudopilus that acts as a piston to extrude exoproteins out of cells. Through structure...
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Full title
Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa
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TN_cdi_plos_journals_2251095886
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251095886
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007343
