Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection
Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Ym1 and RELMα are established effector molecules closely synonymous with Th2-type inflammation and associated pathology. Here, we show that whilst largely dependent on IL-4Rα signaling during a type 2 response, Ym1 and RELMα also have IL-4Rα-independent expression patterns in the lung. Notably, we found that Ym1 has opposing effects on type 2 immun...
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Full title
Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection
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TN_cdi_plos_journals_2251105069
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251105069
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007423
