Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic a...
Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic approaches
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The cited antifungals and fungicides have the following mode of action: polyenes bind ergosterol; phenylpyrroles and dicarboximides inhibit MAP/histidine-kinases; azoles and morpholines target 14α-lanosterol demethylase and both sterol Δ14-reductase and Δ8-Δ7-isomerase, respectively (both chemical classes are used in medicine and in the environment...
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Full title
Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic approaches
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TN_cdi_plos_journals_2251133098
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251133098
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007478
