Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate exp...
Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8+ T cell effector function
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Varicella zoster virus (VZV) is a lymphotropic alpha-herpesvirinae subfamily member that produces varicella on primary infection and causes zoster, vascular disease and vision loss upon reactivation from latency. VZV-infected peripheral blood mononuclear cells (PBMCs) disseminate virus to distal organs to produce clinical disease. To assess immune...
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Full title
Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8+ T cell effector function
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TN_cdi_plos_journals_2251133702
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251133702
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007650
