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MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphy...

MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251143626

MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis

About this item

Full title

MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2019-04, Vol.15 (4), p.e1007744-e1007744

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Staphylococcus aureus is able to infect virtually all organ systems and is a frequently isolated etiologic agent of osteomyelitis, a common and debilitating invasive infection of bone. Treatment of osteomyelitis requires invasive surgical procedures and prolonged antibiotic therapy, yet is frequently unsuccessful due to extensive pathogen-induced b...

Alternative Titles

Full title

MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2251143626

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251143626

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1007744

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