Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycosi...
Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Antibiotic susceptibility of bacterial pathogens is typically evaluated using in vitro assays that do not consider the complex host microenvironment. This may help explaining a significant discrepancy between antibiotic efficacy in vitro and in vivo, with some antibiotics being effective in vitro but not in vivo or vice versa. Nevertheless, it is w...
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Full title
Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics
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TN_cdi_plos_journals_2251143694
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251143694
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007697
