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Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk h...

Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk h...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251153535

Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance

About this item

Full title

Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2019-05, Vol.15 (5), p.e1007755

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Human papillomaviruses (HPV) have genotype-specific disease associations, with high-risk alpha types causing at least 5% of all human cancers. Despite these conspicuous differences, our data show that high- and low- risk HPV types use similar approaches for genome maintenance and persistence. During the maintenance phase, viral episomes and the hos...

Alternative Titles

Full title

Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2251153535

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251153535

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1007755

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