The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like recepto...
The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming
About this item
Full title
Author / Creator
Sardinha-Silva, Aline , Mendonça-Natividade, Flávia C. , Pinzan, Camila F. , Lopes, Carla D. , Costa, Diego L. , Jacot, Damien , Fernandes, Fabricio F. , Zorzetto-Fernandes, André L. V. , Gay, Nicholas J. , Sher, Alan , Jankovic, Dragana , Soldati-Favre, Dominique , Grigg, Michael E. and Roque-Barreira, Maria Cristina
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Infection of host cells by Toxoplasma gondii is an active process, which is regulated by secretion of microneme (MICs) and rhoptry proteins (ROPs and RONs) from specialized organelles in the apical pole of the parasite. MIC1, MIC4 and MIC6 assemble into an adhesin complex secreted on the parasite surface that functions to promote infection competen...
Alternative Titles
Full title
The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2251162075
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251162075
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007871
