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The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promot...

The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promot...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251162087

The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis

About this item

Full title

The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2019-06, Vol.15 (6), p.e1007848-e1007848

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Streptococcus agalactiae (Group B Streptococcus, GBS) normally colonizes healthy adults but can cause invasive disease, such as meningitis, in the newborn. To gain access to the central nervous system, GBS must interact with and penetrate brain or meningeal blood vessels; however, the exact mechanisms are still being elucidated. Here, we investigat...

Alternative Titles

Full title

The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2251162087

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251162087

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1007848

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