The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promot...
The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Streptococcus agalactiae (Group B Streptococcus, GBS) normally colonizes healthy adults but can cause invasive disease, such as meningitis, in the newborn. To gain access to the central nervous system, GBS must interact with and penetrate brain or meningeal blood vessels; however, the exact mechanisms are still being elucidated. Here, we investigat...
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The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis
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TN_cdi_plos_journals_2251162087
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251162087
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007848