Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosp...
Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
There is need for a more efficient cell-based assay amenable to high-throughput drug screening against Giardia lamblia. Here, we report the development of a screening method utilizing G. lamblia engineered to express red-shifted firefly luciferase. Parasite growth and replication were quantified using D-luciferin as a substrate in a bioluminescent...
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Full title
Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum
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TN_cdi_plos_journals_2252291073
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2252291073
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ISSN
1935-2735,1935-2727
E-ISSN
1935-2735
DOI
10.1371/journal.pntd.0006673
