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Quantification of dengue virus specific T cell responses and correlation with viral load and clinica...

Quantification of dengue virus specific T cell responses and correlation with viral load and clinica...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2252302047

Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infection

About this item

Full title

Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infection

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2018-10, Vol.12 (10), p.e0006540-e0006540

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In order to understand the role of dengue virus (DENV) specific T cell responses that associate with protection, we studied their frequency and phenotype in relation to clinical disease severity and resolution of viraemia in a large cohort of patients with varying severity of acute dengue infection.
Using ex vivo IFNγ ELISpot assays we determine...

Alternative Titles

Full title

Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2252302047

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2252302047

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0006540

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