Inhibition of Polo-like kinase 2 ameliorates pathogenesis in Alzheimer’s disease model mice
Inhibition of Polo-like kinase 2 ameliorates pathogenesis in Alzheimer’s disease model mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Alzheimer disease (AD) is a neurodegenerative disorder characterized by pathological hallmarks of neurofibrillary tangles and amyloid plaques. The plaques are formed by aggregation and accumulation of amyloid β (Aβ), a cleavage fragment of amyloid precursor protein (APP). Enhanced neuronal activity and seizure events are frequently observed in AD,...
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Full title
Inhibition of Polo-like kinase 2 ameliorates pathogenesis in Alzheimer’s disease model mice
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TN_cdi_plos_journals_2258360412
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2258360412
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0219691
