Detecting T cell receptors involved in immune responses from single repertoire snapshots
Detecting T cell receptors involved in immune responses from single repertoire snapshots
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Hypervariable T cell receptors (TCRs) play a key role in adaptive immunity, recognizing a vast diversity of pathogen-derived antigens. Our ability to extract clinically relevant information from large high-throughput sequencing of TCR repertoires (RepSeq) data is limited, because little is known about TCR-disease associations. We present Antigen-sp...
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Full title
Detecting T cell receptors involved in immune responses from single repertoire snapshots
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TN_cdi_plos_journals_2258795495
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2258795495
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3000314