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Detecting T cell receptors involved in immune responses from single repertoire snapshots

Detecting T cell receptors involved in immune responses from single repertoire snapshots

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2258795495

Detecting T cell receptors involved in immune responses from single repertoire snapshots

About this item

Full title

Detecting T cell receptors involved in immune responses from single repertoire snapshots

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2019-06, Vol.17 (6), p.e3000314-e3000314

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Hypervariable T cell receptors (TCRs) play a key role in adaptive immunity, recognizing a vast diversity of pathogen-derived antigens. Our ability to extract clinically relevant information from large high-throughput sequencing of TCR repertoires (RepSeq) data is limited, because little is known about TCR-disease associations. We present Antigen-sp...

Alternative Titles

Full title

Detecting T cell receptors involved in immune responses from single repertoire snapshots

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2258795495

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2258795495

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3000314

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