Quick assessment for systematic test statistic inflation/deflation due to null model misspecificatio...
Quick assessment for systematic test statistic inflation/deflation due to null model misspecifications in genome-wide environment interaction studies
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Gene-environment (GxE) interaction is one potential explanation for the missing heritability problem. A popular approach to genome-wide environment interaction studies (GWEIS) is based on regression models involving interactions between genetic variants and environment variables. Unfortunately, GWEIS encounters systematically inflated (or deflated)...
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Full title
Quick assessment for systematic test statistic inflation/deflation due to null model misspecifications in genome-wide environment interaction studies
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TN_cdi_plos_journals_2260274638
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2260274638
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0219825
