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Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regula...

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regula...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2272251123

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action

About this item

Full title

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-08, Vol.14 (8), p.e0220717-e0220717

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT) and the nuclear receptor co-repressor1 (NCoR1) are paralogs and regulate nuclear receptor (NR) function through the recruitment of a multiprotein complex that includes histone deacetylase activity. Previous genetic strategies which deleted SMRT in a specific tissue or which altered...

Alternative Titles

Full title

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2272251123

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2272251123

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0220717

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