Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model
Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Direct conversion from fibroblasts to generate hepatocyte like-cells (iHeps) bypassing the pluripotent state has been described in previous reports as an attractive method acquiring hepatocytes for cell-based therapy. The limited proliferation of iHeps, however, has hampered it uses in cell-based therapy. Since hepatic stem cells (HepSCs) possess s...
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Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model
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TN_cdi_plos_journals_2272251180
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2272251180
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0221085
