PCR-free whole exome sequencing: Cost-effective and efficient in detecting rare mutations
PCR-free whole exome sequencing: Cost-effective and efficient in detecting rare mutations
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
In this study, we describe the development of a PCR-free whole exome sequencing method. Using this method, 2 μg DNA was sufficient for library preparation for whole exome sequencing. Furthermore, the method is simple and makes use of a commercial kit, with additional step of concentrating the captured library by ethanol precipitation. The accuracy...
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Full title
PCR-free whole exome sequencing: Cost-effective and efficient in detecting rare mutations
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TN_cdi_plos_journals_2290061806
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2290061806
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0222562
