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DKK1 promotes hepatocellular carcinoma inflammation, migration and invasion: Implication of TGF-β1

DKK1 promotes hepatocellular carcinoma inflammation, migration and invasion: Implication of TGF-β1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2299562291

DKK1 promotes hepatocellular carcinoma inflammation, migration and invasion: Implication of TGF-β1

About this item

Full title

DKK1 promotes hepatocellular carcinoma inflammation, migration and invasion: Implication of TGF-β1

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-09, Vol.14 (9), p.e0223252-e0223252

Language

English

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Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Dickkopf-1 (DKK1), an inhibitor of the most frequently impaired signaling pathway in hepatocellular carcinoma (HCC), the Wnt/beta-catenin pathway, seems to fulfill contradictory functions in the process of tumorigenesis, acting either as an oncogenic promoter of metastasis or as a tumor suppressor. Elevated serum levels of DKK1 have been reported i...

Alternative Titles

Full title

DKK1 promotes hepatocellular carcinoma inflammation, migration and invasion: Implication of TGF-β1

Authors, Artists and Contributors

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Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2299562291

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2299562291

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0223252

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