Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis
Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The interplay between signalling pathways and metabolism is crucial for tissue growth. Yet, it remains poorly understood. Here, we studied the consequences of modulating iron metabolism on the growth of Drosophila imaginal discs. We find that reducing the levels of the ferritin heavy chain in the larval wing discs leads to drastic growth defects, w...
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Full title
Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis
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TN_cdi_plos_journals_2306303823
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2306303823
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1008396
