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An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug res...

An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug res...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2306488613

An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug resistance in high grade pancreatic ductal adenocarcinoma

About this item

Full title

An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug resistance in high grade pancreatic ductal adenocarcinoma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-10, Vol.14 (10), p.e0223554

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Pancreatic ductal adenocarcinoma (PDAC) is notoriously difficult to treat due to its aggressive, ever resilient nature. A major drawback lies in its tumor grade; a phenomenon observed across various carcinomas, where highly differentiated and undifferentiated tumor grades, termed as low and high grade respectively, are found in the same tumor. One...

Alternative Titles

Full title

An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug resistance in high grade pancreatic ductal adenocarcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2306488613

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2306488613

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0223554

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