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Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2314604477

Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

About this item

Full title

Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2019-10, Vol.17 (10), p.e3000457-e3000457

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Migratory cells use distinct motility modes to navigate different microenvironments, but it is unclear whether these modes rely on the same core set of polarity components. To investigate this, we disrupted actin-related protein 2/3 (Arp2/3) and the WASP-family verprolin homologous protein (WAVE) complex, which assemble branched actin networks that...

Alternative Titles

Full title

Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2314604477

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2314604477

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3000457

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