Cell confinement reveals a branched-actin independent circuit for neutrophil polarity
Cell confinement reveals a branched-actin independent circuit for neutrophil polarity
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Migratory cells use distinct motility modes to navigate different microenvironments, but it is unclear whether these modes rely on the same core set of polarity components. To investigate this, we disrupted actin-related protein 2/3 (Arp2/3) and the WASP-family verprolin homologous protein (WAVE) complex, which assemble branched actin networks that...
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Cell confinement reveals a branched-actin independent circuit for neutrophil polarity
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TN_cdi_plos_journals_2314604477
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2314604477
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3000457