Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection
Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Ebola virus (EBOV) infections are characterized by a pronounced lymphopenia that is highly correlative with fatalities. However, the mechanisms leading to T-cell depletion remain largely unknown. Here, we demonstrate that both viral mRNAs and antigens are detectable in CD4+ T cells despite the absence of productive infection. A protein phosphatase...
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Full title
Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection
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TN_cdi_plos_journals_2314933793
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2314933793
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1008068
