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Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interst...

Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interst...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2319185424

Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood–brain-barrier permeability

About this item

Full title

Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood–brain-barrier permeability

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-11, Vol.14 (11), p.e0225760

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Even though HIV-1 replication can be suppressed by combination antiretroviral therapy (cART) inflammatory processes still occur, contributing to comorbidities. Comorbidities are attributed to variety of factors, including HIV-1 mediated inflammation. Several HIV-1 proteins mediate central nervous system (CNS) inflammation, including Nef. Nef is an...

Alternative Titles

Full title

Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood–brain-barrier permeability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2319185424

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2319185424

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0225760

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