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Chronic dietary supplementation with kynurenic acid, a neuroactive metabolite of tryptophan, decreas...

Chronic dietary supplementation with kynurenic acid, a neuroactive metabolite of tryptophan, decreas...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2322377030

Chronic dietary supplementation with kynurenic acid, a neuroactive metabolite of tryptophan, decreased body weight without negative influence on densitometry and mandibular bone biomechanical endurance in young rats

About this item

Full title

Chronic dietary supplementation with kynurenic acid, a neuroactive metabolite of tryptophan, decreased body weight without negative influence on densitometry and mandibular bone biomechanical endurance in young rats

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-12, Vol.14 (12), p.e0226205-e0226205

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Kynurenic acid (KYNA) is a neuroactive metabolite of tryptophan. KYNA naturally occurs in breast milk and its content increases with lactation, indicating the role of neonatal nutrition in general growth with long-term health effects. KYNA is also an antagonist of ionotropic glutamate receptors expressed in bone cells. The aim of this study was to...

Alternative Titles

Full title

Chronic dietary supplementation with kynurenic acid, a neuroactive metabolite of tryptophan, decreased body weight without negative influence on densitometry and mandibular bone biomechanical endurance in young rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2322377030

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2322377030

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0226205

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