Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequ...
Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Despite genetics being accepted as the primary cause of familial aggregation for most diseases, it is still unclear whether afflicted families are likely to share a single highly penetrant rare variant, many minimally penetrant common variants, or a combination of the two types of variants. We therefore use recent estimates of SNP heritability and...
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Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies
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TN_cdi_plos_journals_2327569541
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2327569541
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1008490
