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Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nucle...

Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nucle...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2335631013

Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA

About this item

Full title

Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-01, Vol.15 (1), p.e0227520

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Glucocorticoid (GR) and mineralocorticoid receptors (MR) are believed to classically bind DNA as homodimers or MR-GR heterodimers to influence gene regulation in response to pulsatile basal or stress-evoked glucocorticoid secretion. Pulsed corticosterone presentation reveals MR and GR co-occupy DNA only at the peaks of glucocorticoid oscillations,...

Alternative Titles

Full title

Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2335631013

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2335631013

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0227520

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