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Liganded T3 receptor β2 inhibits the positive feedback autoregulation of the gene for GATA2, a trans...

Liganded T3 receptor β2 inhibits the positive feedback autoregulation of the gene for GATA2, a trans...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2338987991

Liganded T3 receptor β2 inhibits the positive feedback autoregulation of the gene for GATA2, a transcription factor critical for thyrotropin production

About this item

Full title

Liganded T3 receptor β2 inhibits the positive feedback autoregulation of the gene for GATA2, a transcription factor critical for thyrotropin production

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-01, Vol.15 (1), p.e0227646-e0227646

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The serum concentration of thyrotropin (thyroid stimulating hormone, TSH) is drastically reduced by small increase in the levels of thyroid hormones (T3 and its prohormone, T4); however, the mechanism underlying this relationship is unknown. TSH consists of the chorionic gonadotropin α (CGA) and the β chain (TSHβ). The expression of both peptides i...

Alternative Titles

Full title

Liganded T3 receptor β2 inhibits the positive feedback autoregulation of the gene for GATA2, a transcription factor critical for thyrotropin production

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2338987991

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2338987991

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0227646

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