Cytoplasmic factories, virus assembly, and DNA replication kinetics collectively constrain the forma...
Cytoplasmic factories, virus assembly, and DNA replication kinetics collectively constrain the formation of poxvirus recombinants
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Poxviruses replicate in cytoplasmic structures called factories and each factory begins as a single infecting particle. Sixty-years ago Cairns predicted that this might have effects on vaccinia virus (VACV) recombination because the factories would have to collide and mix their contents to permit recombination. We've since shown that factories coll...
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Cytoplasmic factories, virus assembly, and DNA replication kinetics collectively constrain the formation of poxvirus recombinants
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TN_cdi_plos_journals_2339787738
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2339787738
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0228028