Astrocyte senescence promotes glutamate toxicity in cortical neurons
Astrocyte senescence promotes glutamate toxicity in cortical neurons
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Neurodegeneration is a major age-related pathology. Cognitive decline is characteristic of patients with Alzheimer's and related dementias and cancer patients after chemo- or radio-therapies. A recently emerged driver of these and other age-related pathologies is cellular senescence, a cell fate that entails a permanent cell cycle arrest and pro-in...
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Full title
Astrocyte senescence promotes glutamate toxicity in cortical neurons
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TN_cdi_plos_journals_2339787883
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2339787883
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0227887
