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Viral FLIP blocks Caspase-8 driven apoptosis in the gut in vivo

Viral FLIP blocks Caspase-8 driven apoptosis in the gut in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2348788438

Viral FLIP blocks Caspase-8 driven apoptosis in the gut in vivo

About this item

Full title

Viral FLIP blocks Caspase-8 driven apoptosis in the gut in vivo

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-01, Vol.15 (1), p.e0228441-e0228441

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

A strict cell death control in the intestinal epithelium is indispensable to maintain barrier integrity and homeostasis. In order to achieve a balance between cell proliferation and cell death, a tight regulation of Caspase-8, which is a key player in controlling apoptosis, is required. Caspase-8 activity is regulated by cellular FLIP proteins. The...

Alternative Titles

Full title

Viral FLIP blocks Caspase-8 driven apoptosis in the gut in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2348788438

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2348788438

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0228441

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