Intramuscular vaccination of mice with the human herpes simplex virus type-1(HSV-1) VC2 vaccine, but...
Intramuscular vaccination of mice with the human herpes simplex virus type-1(HSV-1) VC2 vaccine, but not its parental strain HSV-1(F) confers full protection against lethal ocular HSV-1 (McKrae) pathogenesis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Herpes simplex virus type-1 (HSV-1) can cause severe ocular infection and blindness. We have previously shown that the HSV-1 VC2 vaccine strain is protective in mice and guinea pigs against genital herpes infection following vaginal challenge with HSV-1 or HSV-2. In this study, we evaluated the efficacy of VC2 intramuscular vaccination in mice agai...
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Full title
Intramuscular vaccination of mice with the human herpes simplex virus type-1(HSV-1) VC2 vaccine, but not its parental strain HSV-1(F) confers full protection against lethal ocular HSV-1 (McKrae) pathogenesis
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TN_cdi_plos_journals_2352045203
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2352045203
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0228252