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Simultaneous quantification of palbociclib, ribociclib and letrozole in human plasma by a new LC-MS/...

Simultaneous quantification of palbociclib, ribociclib and letrozole in human plasma by a new LC-MS/...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2352320928

Simultaneous quantification of palbociclib, ribociclib and letrozole in human plasma by a new LC-MS/MS method for clinical application

About this item

Full title

Simultaneous quantification of palbociclib, ribociclib and letrozole in human plasma by a new LC-MS/MS method for clinical application

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-02, Vol.15 (2), p.e0228822-e0228822

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

A novel LC-MS/MS method was developed for the quantification of the new cyclin dependent kinase inhibitors (CDKIs) palbociclib and ribociclib and the aromatase inhibitor letrozole used in combinatory regimen. The proposed method is appropriate to be applied in clinical practice due to the simple and fast sample preparation based on protein precipit...

Alternative Titles

Full title

Simultaneous quantification of palbociclib, ribociclib and letrozole in human plasma by a new LC-MS/MS method for clinical application

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2352320928

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2352320928

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0228822

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