How the initiating ribosome copes with ppGpp to translate mRNAs
How the initiating ribosome copes with ppGpp to translate mRNAs
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United States: Public Library of Science
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English
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United States: Public Library of Science
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During host colonization, bacteria use the alarmones (p)ppGpp to reshape their proteome by acting pleiotropically on DNA, RNA, and protein synthesis. Here, we elucidate how the initiating ribosome senses the cellular pool of guanosine nucleotides and regulates the progression towards protein synthesis. Our results show that the affinity of guanosin...
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Full title
How the initiating ribosome copes with ppGpp to translate mRNAs
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TN_cdi_plos_journals_2355994383
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2355994383
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3000593
