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Oligoclonal IgG antibodies in multiple sclerosis target patient-specific peptides

Oligoclonal IgG antibodies in multiple sclerosis target patient-specific peptides

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2360073610

Oligoclonal IgG antibodies in multiple sclerosis target patient-specific peptides

About this item

Full title

Oligoclonal IgG antibodies in multiple sclerosis target patient-specific peptides

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-02, Vol.15 (2), p.e0228883-e0228883

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

IgG oligoclonal bands (OCBs) are present in the cerebrospinal fluid (CSF) of more than 95% of patients with multiple sclerosis (MS), and are considered to be the immunological hallmark of disease. However, the target specificities of the IgG in MS OCBs have remained undiscovered. Nevertheless, evidence that OCBs are associated with increased levels...

Alternative Titles

Full title

Oligoclonal IgG antibodies in multiple sclerosis target patient-specific peptides

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2360073610

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2360073610

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0228883

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