Lack of an association between clinical INSTI-related body weight gain and direct interference with...
Lack of an association between clinical INSTI-related body weight gain and direct interference with MC4 receptor (MC4R), a key central regulator of body weight
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
An increasing prevalence of overweight and obesity in people living with HIV has been associated with initiation of antiretroviral therapy with integrase strand transfer inhibitors (INSTIs). An off-target inhibition of the endogenous ligand binding to the human melanocortin 4 receptor (MC4R) has been suggested as a potential mechanism for clinical...
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Full title
Lack of an association between clinical INSTI-related body weight gain and direct interference with MC4 receptor (MC4R), a key central regulator of body weight
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TN_cdi_plos_journals_2367844348
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2367844348
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0229617