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Lack of an association between clinical INSTI-related body weight gain and direct interference with...

Lack of an association between clinical INSTI-related body weight gain and direct interference with...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2367844348

Lack of an association between clinical INSTI-related body weight gain and direct interference with MC4 receptor (MC4R), a key central regulator of body weight

About this item

Full title

Lack of an association between clinical INSTI-related body weight gain and direct interference with MC4 receptor (MC4R), a key central regulator of body weight

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-02, Vol.15 (2), p.e0229617-e0229617

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

An increasing prevalence of overweight and obesity in people living with HIV has been associated with initiation of antiretroviral therapy with integrase strand transfer inhibitors (INSTIs). An off-target inhibition of the endogenous ligand binding to the human melanocortin 4 receptor (MC4R) has been suggested as a potential mechanism for clinical...

Alternative Titles

Full title

Lack of an association between clinical INSTI-related body weight gain and direct interference with MC4 receptor (MC4R), a key central regulator of body weight

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2367844348

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2367844348

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0229617

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