Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization...
Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast
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Au, Wei-Chun , Zhang, Tianyi , Mishra, Prashant K. , Eisenstatt, Jessica R. , Walker, Robert L. , Ocampo, Josefina , Dawson, Anthony , Warren, Jack , Costanzo, Michael , Baryshnikova, Anastasia , Flick, Karin , Clark, David J. , Meltzer, Paul S. , Baker, Richard E. , Myers, Chad , Boone, Charles , Kaiser, Peter and Basrai, Munira A.
Publisher
United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Restricting the localization of the histone H3 variant CENP-A (Cse4 in yeast, CID in flies) to centromeres is essential for faithful chromosome segregation. Mislocalization of CENP-A leads to chromosomal instability (CIN) in yeast, fly and human cells. Overexpression and mislocalization of CENP-A has been observed in many cancers and this correlate...
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Full title
Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast
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TN_cdi_plos_journals_2377704909
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2377704909
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1008597
