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Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disea...

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disea...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2390757668

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease

About this item

Full title

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2020-03, Vol.16 (3), p.e1008604

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The influence of environmental insults on the onset and progression of mitochondrial diseases is unknown. To evaluate the effects of infection on mitochondrial disease we used a mouse model of Leigh Syndrome, where a missense mutation in the Taco1 gene results in the loss of the translation activator of cytochrome c oxidase subunit I (TACO1) protei...

Alternative Titles

Full title

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2390757668

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2390757668

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1008604

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