XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathway...
XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Scope and Contents
Contents
Loss of the XPF-ERCC1 endonuclease causes a dramatic phenotype that results in progeroid features associated with liver, kidney and bone marrow dysfunction. As this nuclease is involved in multiple DNA repair transactions, it is plausible that this severe phenotype results from the simultaneous inactivation of both branches of nucleotide excision r...
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Full title
XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways
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TN_cdi_plos_journals_2403774483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2403774483
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1008555
