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XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathway...

XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathway...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2403774483

XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways

About this item

Full title

XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2020-04, Vol.16 (4), p.e1008555-e1008555

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Loss of the XPF-ERCC1 endonuclease causes a dramatic phenotype that results in progeroid features associated with liver, kidney and bone marrow dysfunction. As this nuclease is involved in multiple DNA repair transactions, it is plausible that this severe phenotype results from the simultaneous inactivation of both branches of nucleotide excision r...

Alternative Titles

Full title

XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2403774483

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2403774483

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1008555

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