XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathway...
XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Loss of the XPF-ERCC1 endonuclease causes a dramatic phenotype that results in progeroid features associated with liver, kidney and bone marrow dysfunction. As this nuclease is involved in multiple DNA repair transactions, it is plausible that this severe phenotype results from the simultaneous inactivation of both branches of nucleotide excision r...
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XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways
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TN_cdi_plos_journals_2403774483
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2403774483
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1008555