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Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration

Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2403776243

Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration

About this item

Full title

Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2020-04, Vol.16 (4), p.e1008496-e1008496

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Human herpesviruses 6A and 6B (HHV-6A/B) are unique among human herpesviruses in their ability to integrate their genome into host chromosomes. Viral integration occurs at the ends of chromosomes within the host telomeres. The ends of the HHV-6A/B genomes contain telomeric repeats that facilitate the integration process. Here, we report that produc...

Alternative Titles

Full title

Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2403776243

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2403776243

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1008496

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