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Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternati...

Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2405599522

Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing

About this item

Full title

Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-05, Vol.15 (5), p.e0233380-e0233380

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Alternative mRNA splicing increases protein diversity, and alternative splicing events (ASEs) drive oncogenesis in multiple tumor types. However, the driving alterations that underlie the broad dysregulation of ASEs are incompletely defined. Using head and neck squamous cell carcinoma (HNSCC) as a model, we hypothesized that the genomic alteration...

Alternative Titles

Full title

Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2405599522

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2405599522

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0233380

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