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Amyloid β induces interneuron-specific changes in the hippocampus of APPNL-F mice

Amyloid β induces interneuron-specific changes in the hippocampus of APPNL-F mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2407761750

Amyloid β induces interneuron-specific changes in the hippocampus of APPNL-F mice

About this item

Full title

Amyloid β induces interneuron-specific changes in the hippocampus of APPNL-F mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020, Vol.15 (5), p.e0233700-e0233700

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and amyloid-beta (Aβ) depositions generated by the proteolysis of amyloid precursor protein (APP) in the brain. In APPNL-F mice, APP gene was humanized and contains two familial AD mutations, and APP-unlike other mouse models of AD-is driven by the endogenou...

Alternative Titles

Full title

Amyloid β induces interneuron-specific changes in the hippocampus of APPNL-F mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2407761750

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2407761750

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0233700

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