Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis
Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Extracellular adenosine triphosphate (eATP) released by damaged cells, and its purinergic receptors, comprise a crucial signaling network after injury. Purinergic receptor P2X7 (P2RX7), a major driver of NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activation and IL-1β processing, has been shown to play a role in liver in...
Alternative Titles
Full title
Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2409181211
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2409181211
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0234038
