An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncog...
An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis
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San Francisco: Public Library of Science
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Language
English
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Publisher
San Francisco: Public Library of Science
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Contents
The presence of the chimeric EWSR1-FLI1 oncoprotein is the main and initiating event defining Ewing sarcoma (ES). The dysregulation of epigenomic and proteomic homeostasis induced by the oncoprotein contributes to a wide variety of events involved in oncogenesis and tumor progression. Attempts at studying the effects of EWSR1-FLI1 in non-tumor cell...
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Full title
An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis
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TN_cdi_plos_journals_2409870259
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2409870259
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0234243
