Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental a...
Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental autoimmune encephalitis in rodents
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Publisher
San Francisco: Public Library of Science
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Language
English
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Publisher
San Francisco: Public Library of Science
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Contents
Multiple sclerosis (MS) is a neurodegenerative disease characterized by demyelination and inflammation. Dysregulated lipid metabolism and mitochondrial dysfunction are hypothesized to play a key role in MS. Carnitine Palmitoyl Transferase 1 (CPT1) is a rate-limiting enzyme for beta-oxidation of fatty acids in mitochondria. The therapeutic effect of...
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Full title
Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental autoimmune encephalitis in rodents
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TN_cdi_plos_journals_2411517304
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2411517304
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0234493
