Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner
Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner
About this item
Full title
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Publisher
San Francisco: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
San Francisco: Public Library of Science
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Scope and Contents
Contents
Renal dysplasia, the major cause of childhood renal failure, is characterized by defective branching morphogenesis and nephrogenesis. Beta-catenin, a transcription factor and cell adhesion molecule, is markedly increased in the nucleus of kidney cells in human renal dysplasia and contributes to its pathogenesis by altering target genes that are ess...
Alternative Titles
Full title
Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner
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Record Identifier
TN_cdi_plos_journals_2414405483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2414405483
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0234375
