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miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor i...

miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2414405556

miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor in melanoma

About this item

Full title

miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor in melanoma

Publisher

San Francisco: Public Library of Science

Journal title

PloS one, 2020-06, Vol.15 (6), p.e0234707

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Despite significant development of melanoma therapies, death rates remain high. MicroRNAs, controlling posttranscriptionally gene expression, play role in development of resistance to BRAF inhibitors. The aim of the study was to assess the role of miR-410-3p in response to vemurafenib-BRAF inhibitor. FFPE tissue samples of 12 primary nodular melano...

Alternative Titles

Full title

miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor in melanoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2414405556

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2414405556

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0234707

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