Structural and functional features of medium spiny neurons in the BACHDΔN17 mouse model of Huntingto...
Structural and functional features of medium spiny neurons in the BACHDΔN17 mouse model of Huntington’s Disease
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San Francisco: Public Library of Science
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English
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San Francisco: Public Library of Science
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In the BACHD mouse model of Huntington’s disease (HD), deletion of the N17 domain of the Huntingtin gene (BACHDΔN17, Q97) has been reported to lead to nuclear accumulation of mHTT and exacerbation of motor deficits, neuroinflammation and striatal atrophy (Gu et al., 2015). Here we characterized the effect of N17 deletion on dorsolateral striatal me...
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Structural and functional features of medium spiny neurons in the BACHDΔN17 mouse model of Huntington’s Disease
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TN_cdi_plos_journals_2416237639
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2416237639
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0234394
